miR-190-Mediated Downregulation of PHLPP Contributes to Arsenic-Induced Akt Activation and Carcinogenesis

The role of trivalent arsenic (As(3+)) on the regulation of the recently identified noncoding small RNAs, mainly microRNAs, has not been explored so far. In the present study, we provide evidence showing that As(3+) is a potent inducer for the expression of miR-190 in human bronchial epithelial cell...

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Bibliografische gegevens
Hoofdauteurs: Beezhold, Kevin, Liu, Jia, Kan, Hong, Meighan, Terry, Castranova, Vince, Shi, Xianglin, Chen, Fei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2011
Onderwerpen:
Carcinogenicity
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179680/
https://ncbi.nlm.nih.gov/pubmed/21750348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr188
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