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NF-κB1 p50 promotes p53 protein translation through miR-190 downregulation of PHLPP1

The biological function of NF-κB1 (p50) in the regulation of protein expression is far from well understood owing to the lack of a transcriptional domain. Here, we report a novel function of p50 in its regulation of p53 protein translation under stress conditions. We found that the deletion of p50 (...

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Bibliografiska uppgifter
Huvudupphovsmän: Yu, Y, Zhang, D, Huang, H, Li, J, Zhang, M, Wan, Y, Gao, J, Huang, C
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883870/
https://ncbi.nlm.nih.gov/pubmed/23396362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.8
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