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No Effect of Folic Acid Supplementation on Global DNA Methylation in Men and Women with Moderately Elevated Homocysteine

A global loss of cytosine methylation in DNA has been implicated in a wide range of diseases. There is growing evidence that modifications in DNA methylation can be brought about by altering the intake of methyl donors such as folate. We examined whether long-term daily supplementation with 0.8 mg o...

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Detalhes bibliográficos
Main Authors: Jung, Audrey Y., Smulders, Yvo, Verhoef, Petra, Kok, Frans J., Blom, Henk, Kok, Robert M., Kampman, Ellen, Durga, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179474/
https://ncbi.nlm.nih.gov/pubmed/21966393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024976
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