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No Effect of Folic Acid Supplementation on Global DNA Methylation in Men and Women with Moderately Elevated Homocysteine

A global loss of cytosine methylation in DNA has been implicated in a wide range of diseases. There is growing evidence that modifications in DNA methylation can be brought about by altering the intake of methyl donors such as folate. We examined whether long-term daily supplementation with 0.8 mg o...

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Autors principals: Jung, Audrey Y., Smulders, Yvo, Verhoef, Petra, Kok, Frans J., Blom, Henk, Kok, Robert M., Kampman, Ellen, Durga, Jane
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179474/
https://ncbi.nlm.nih.gov/pubmed/21966393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024976
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