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No Effect of Folic Acid Supplementation on Global DNA Methylation in Men and Women with Moderately Elevated Homocysteine

A global loss of cytosine methylation in DNA has been implicated in a wide range of diseases. There is growing evidence that modifications in DNA methylation can be brought about by altering the intake of methyl donors such as folate. We examined whether long-term daily supplementation with 0.8 mg o...

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Библиографические подробности
Главные авторы: Jung, Audrey Y., Smulders, Yvo, Verhoef, Petra, Kok, Frans J., Blom, Henk, Kok, Robert M., Kampman, Ellen, Durga, Jane
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179474/
https://ncbi.nlm.nih.gov/pubmed/21966393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024976
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