Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression

Genetic variation is thought to contribute to variability in platelet function; however, the specific variants and mechanisms that contribute to altered platelet function are poorly defined. With the use of a combination of fine mapping and sequencing of the platelet endothelial aggregation receptor...

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מידע ביבליוגרפי
Main Authors: Faraday, Nauder, Yanek, Lisa R., Yang, Xiao Ping, Mathias, Rasika, Herrera-Galeano, J. Enrique, Suktitipat, Bhoom, Qayyum, Rehan, Johnson, Andrew D., Chen, Ming-Huei, Tofler, Geoffrey H., Ruczinski, Ingo, Friedman, Alan D., Gylfason, Arnaldur, Thorsteinsdottir, Unnur, Bray, Paul F., O'Donnell, Christopher J., Becker, Diane M., Becker, Lewis C.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2011
נושאים:
Platelets and Thrombopoiesis
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179402/
https://ncbi.nlm.nih.gov/pubmed/21791418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-320788
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