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Rituximab infusion induces NK activation in lymphoma patients with the high-affinity CD16 polymorphism
Natural killer (NK) cell–mediated antibody-dependent cellular cytotoxicity involving FcγRIIIa (CD16) likely contributes to the clinical efficacy of rituximab. To assess the in vivo effects of CD16 polymorphisms on rituximab-induced NK activation, blood was evaluated before and 4 hours after initiati...
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Autori principali: | , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society of Hematology
2011
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3179401/ https://ncbi.nlm.nih.gov/pubmed/21768303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-351411 |
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