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Mutations in two regions upstream of the A gamma globin gene canonical promoter affect gene expression.

Two regions upstream of the human fetal (A gamma) globin gene, which interact with protein factors from K562 and HeLa nuclear extracts, have functional significance in gene expression. One binding site (site I) is at a position -290 to -267 bp upstream of the transcription initiation site, the other...

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Publicat a:Nucleic Acids Res
Autors principals: Lloyd, J A, Lee, R F, Lingrel, J B
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1989
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317938/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2472607/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.11.4339
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