ADAM8 Enhances Osteoclast Precursor Fusion and Osteoclast Formation In Vitro and In Vivo

ADAM8 expression is increased in the interface tissue around a loosened hip prosthesis and in the pannus and synovium of patients with rheumatoid arthritis, but its potential role in these processes is unclear. ADAM8 stimulates osteoclast (OCL) formation, but the effects of overexpression or loss of...

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Autors principals: Ishizuka, Hisako, García-Palacios, Verónica, Lu, Ganwei, Subler, Mark A, Zhang, Heju, Boykin, Christina S, Choi, Sun Jin, Zhao, Liena, Patrene, Kenneth, Galson, Deborah L, Blair, Harry C, Hadi, Tamer M, Windle, Jolene J, Kurihara, Noriyoshi, Roodman, G David
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2011
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179311/
https://ncbi.nlm.nih.gov/pubmed/20683884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.199
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