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Development and characterization of nanosuspensions of olmesartan medoxomil for bioavailability enhancement
BACKGROUND: Olmesartan medoxomil (OLM), an anti-hypertensive agent administered orally has absolute bioavailability of only 26% due to the poor aqueous solubility (<7.75 μg/ml). The present investigation aimed at enhancing the oral bioavailability of OLM by improving its solubility and dissolutio...
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Format: | Artigo |
Jezik: | Inglês |
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Medknow Publications Pvt Ltd
2011
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3178951/ https://ncbi.nlm.nih.gov/pubmed/21966165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-7406.84459 |
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