Development and characterization of nanosuspensions of olmesartan medoxomil for bioavailability enhancement

BACKGROUND: Olmesartan medoxomil (OLM), an anti-hypertensive agent administered orally has absolute bioavailability of only 26% due to the poor aqueous solubility (<7.75 μg/ml). The present investigation aimed at enhancing the oral bioavailability of OLM by improving its solubility and dissolutio...

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Hlavní autoři: Thakkar, Hetal Paresh, Patel, Bindesh Vishnubhai, Thakkar, Sneha Piyush
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications Pvt Ltd 2011
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178951/
https://ncbi.nlm.nih.gov/pubmed/21966165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-7406.84459
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