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Identification of a novel effector domain of BIN1 for cancer suppression
Bridging integrator 1 (BIN1) is a nucleocytoplasmic adaptor protein with tumor suppressor properties. The protein interacts with and inhibits the c-MYC transcription factor through the BIN1 MYC-binding domain (MBD). However, in vitro colony formation assays have clearly demonstrated that the MBD is...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3178729/ https://ncbi.nlm.nih.gov/pubmed/21678469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23222 |
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