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Functional analysis of point mutations in the AAUAAA motif of the SV40 late polyadenylation signal.

We have constructed 14 independent point mutations in the conserved AAUAAA element of the SV40 late polyadenylation signal in order to study the recognition and function of alternative polyadenylation signals. A variant RNA containing an AUUAAA was polyadenylated at 20% the level of wild-type substr...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Wilusz, J, Pettine, S M, Shenk, T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 1989
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317868/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543957/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.10.3899
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