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A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates.

A 64-kilodalton (kDa) polypeptide that is cross-linked by UV light specifically to polyadenylation substrate RNAs containing a functional AAUAAA element has been identified previously. Fractionated HeLa nuclear components that can be combined to regenerate efficient and accurate polyadenylation in v...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Wilusz, J, Shenk, T, Takagaki, Y, Manley, J L
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2304466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.3.1244
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