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Selection of sequence elements that substitute for the standard AATAAA motif which signals 3' processing and polyadenylation of late simian virus 40 mRNAs.

A method is described which allows selection of sequences which can substitute for the normal AATAAA hexanucleotide involved in polyadenylation of SV40 late mRNAs. Plaques were generated from viral DNA lacking the motif, forcing acquisition of substitute sequences. Four variants were characterized....

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Main Authors: Swimmer, C, Shenk, T
格式: Artigo
語言:Inglês
出版: 1985
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC322109/
https://ncbi.nlm.nih.gov/pubmed/2866490
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