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THE BROMODOMAIN-CONTAINING GENE BRD2 IS REGULATED AT TRANSCRIPTION, SPLICING, AND TRANSLATION LEVELS
The human BRD2 gene has been linked and associated with a form of common epilepsy and electroencephalographic abnormalities. Disruption of Brd2 in the mouse revealed that it is essential for embryonic neural development and that viable Brd2(+/-) heterozygotes show both decreased GABAergic neuron cou...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3178676/ https://ncbi.nlm.nih.gov/pubmed/21608014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23192 |
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