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The Double Bromodomain-containing Gene Brd2 Is Essential for Embryonic Development in Mouse
The BET sub-family of bromodomain-containing genes is characterized by the presence of two bromodomains and a unique ET domain at their carboxyl termini. Here we show that the founding member of this sub-family, Brd2, is an essential gene by generating a mutant mouse line lacking Brd2 function. Homo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771124/ https://ncbi.nlm.nih.gov/pubmed/19301389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21911 |
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