Invariant NKT cells recognize glycolipids from pathogenic Gram-positive bacteria

Natural killer T (NKT) cells recognize glycolipid antigens presented by CD1d. These cells express an evolutionarily conserved, invariant T cell receptor (TCR), but the forces driving TCR conservation have remained uncertain. Here we show that NKT cells recognize diacylglycerol-containing glycolipids...

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Autors principals: Kinjo, Yuki, Illarionov, Petr, Vela, José Luis, Pei, Bo, Girardi, Enrico, Li, Xiangming, Li, Yali, Imamura, Masakazu, Kaneko, Yukihiro, Okawara, Akiko, Miyazaki, Yoshitsugu, Gómez-Velasco, Anaximandro, Rogers, Paul, Dahesh, Samira, Uchiyama, Satoshi, Khurana, Archana, Kawahara, Kazuyoshi, Yesilkaya, Hasan, Andrew, Peter W., Wong, Chi-Huey, Kawakami, Kazuyoshi, Nizet, Victor, Besra, Gurdyal S., Tsuji, Moriya, Zajonc, Dirk M., Kronenberg, Mitchell
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178673/
https://ncbi.nlm.nih.gov/pubmed/21892173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2096
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