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Proton storage site in bacteriorhodopsin: new insights from QM/MM simulations of microscopic pK(a) and infrared spectra

Identifying the group that acts as the proton storage/loading site is a challenging but important problem for understanding the mechanism of proton pumping in biomolecular proton pumps, such as bacteriorhodopsin (bR) and cytochrome c oxidase. Recent experimental studies of bR propelled the idea that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Goyal, Puja, Ghosh, Nilanjan, Phatak, Prasad, Clemens, Maike, Gaus, Michael, Elstner, Marcus, Cui, Qiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178665/
https://ncbi.nlm.nih.gov/pubmed/21761868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja201568s
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