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Overexpression of Cathepsin Z Contributes to Tumor Metastasis by Inducing Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma

The aim of this study was to characterize the oncogenic function and mechanism of Cathepsin Z (CTSZ) at 20q13.3, a frequently amplified region in hepatocellular carcinoma (HCC). Real-time PCR were used to compare CTSZ expression between paired HCC tumor and non-tumor specimens. CTSZ gene was stably...

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Bibliografski detalji
Glavni autori: Wang, Jian, Chen, Leilei, Li, Yan, Guan, Xin-Yuan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178578/
https://ncbi.nlm.nih.gov/pubmed/21966391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024967
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