Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma

BACKGROUND: SIRT1 is a member of the mammalian sirtuin family with the ability to deacetylate histone and nonhistone proteins. The correlation between SIRT1 expression and tumor metastasis in several types of cancer has aroused widespread concern. This study investigated SIRT1 expression and its pro...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Hao, Chong, Zhu, Peng-Xi, Yang, Xue, Han, Zhi-Peng, Jiang, Jing-Hua, Zong, Chen, Zhang, Xu-Guang, Liu, Wen-Ting, Zhao, Qiu-Dong, Fan, Ting-Ting, Zhang, Li, Wei, Li-Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391082/
https://ncbi.nlm.nih.gov/pubmed/25522783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-978
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