Selective hydrolysis by exo- and endonucleases of phosphodiester bonds adjacent to an apurinic site.
Partial depurination of d-ApA produced two UV260nm-absorbing isomers, d-SpA and d-ApS (where S represents the depurinated deoxyribose sugar), that provided simple model compounds with which to examine, by HPLC, the response of nucleases to phosphodiester bonds flanked 3' or 5' by an apurinic site. T...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1989
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.10.3735 |
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