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Selective hydrolysis by exo- and endonucleases of phosphodiester bonds adjacent to an apurinic site.
Partial depurination of d-ApA produced two UV260nm-absorbing isomers, d-SpA and d-ApS (where S represents the depurinated deoxyribose sugar), that provided simple model compounds with which to examine, by HPLC, the response of nucleases to phosphodiester bonds flanked 3' or 5' by an apurin...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1989
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC317854/ https://ncbi.nlm.nih.gov/pubmed/2543953 |
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