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Solid phase synthesis of oligoribonucleotides using the 1-[(2-chloro-4-methyl)phenyl]-4-methoxypiperidin-4-yl (Ctmp) group for the protection of the 2'-hydroxy functions and the H-phosphonate approach.

The solid phase synthesis of oligoribonucleotides using the H-phosphonate approach and the 1-[(2-chloro-4-methyl)phenyl]-4-methoxypiperidin-4-yl (Ctmp) and dimethoxytrityl (DMTr) groups, respectively, for the protection of the 2'- and 5'-hydroxy functions is described. The use of a new rea...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sakatsume, O, Ohtsuki, M, Takaku, H, Reese, C B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1989
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317850/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2734100/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.10.3689
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