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Solid phase synthesis of oligoribonucleotides using the 1-[(2-chloro-4-methyl)phenyl]-4-methoxypiperidin-4-yl (Ctmp) group for the protection of the 2'-hydroxy functions and the H-phosphonate approach.

The solid phase synthesis of oligoribonucleotides using the H-phosphonate approach and the 1-[(2-chloro-4-methyl)phenyl]-4-methoxypiperidin-4-yl (Ctmp) and dimethoxytrityl (DMTr) groups, respectively, for the protection of the 2'- and 5'-hydroxy functions is described. The use of a new rea...

詳細記述

保存先:
書誌詳細
主要な著者: Sakatsume, O, Ohtsuki, M, Takaku, H, Reese, C B
フォーマット: Artigo
言語:Inglês
出版事項: 1989
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC317850/
https://ncbi.nlm.nih.gov/pubmed/2734100
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