In vitro Analyses of the Dysregulated R206H ALK2 Kinase-FKBP12 Interaction Associated with Heterotopic Ossification in FOP

A single recurrent mutation in the regulatory subdomain of a bone morphogenetic protein type I receptor kinase has been linked to heterotopic ossification in classic fibrodysplasia ossificans progressiva (FOP). As a result of a substitution at 1 residue by only 1 other side chain (Arg206His) in just...

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Detaylı Bibliyografya
Asıl Yazarlar: Groppe, Jay C., Wu, Jingfeng, Shore, Eileen M., Kaplan, Frederick S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: S. Karger AG 2011
Konular:
Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178093/
https://ncbi.nlm.nih.gov/pubmed/21525719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000324230
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