Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9–mediated EMT

Medulloblastomas are the most common malignant tumors of the central nervous system during childhood. Radiation-induced medulloblastoma tumor recurrences are aggressive and metastatic in nature. In the present study, we demonstrate that Gadd45a expression can sensitize medulloblastoma cells to radio...

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Bibliografiske detaljer
Main Authors: Asuthkar, Swapna, Nalla, Arun Kumar, Gondi, Christopher S., Dinh, Dzung H., Gujrati, Meena, Mohanam, Sanjeeva, Rao, Jasti S.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177664/
https://ncbi.nlm.nih.gov/pubmed/21813510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor109
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