An investigation of the structural requirements for ATP hydrolysis and DNA cleavage by the EcoKI Type I DNA restriction and modification enzyme

Type I DNA restriction/modification systems are oligomeric enzymes capable of switching between a methyltransferase function on hemimethylated host DNA and an endonuclease function on unmethylated foreign DNA. They have long been believed to not turnover as endonucleases with the enzyme becoming ina...

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Main Authors: Roberts, Gareth A., Cooper, Laurie P., White, John H., Su, Tsueu-Ju, Zipprich, Jakob T., Geary, Paul, Kennedy, Cowan, Dryden, David T. F.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
Nucleic Acid Enzymes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177214/
https://ncbi.nlm.nih.gov/pubmed/21685455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr480
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