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Unusual 2-aminopurine fluorescence from a complex of DNA and the EcoKI methyltransferase
The methyltransferase, M.EcoKI, recognizes the DNA sequence 5′-AACNNNNNNGTGC-3′ and methylates adenine at the underlined positions. DNA methylation has been shown by crystallography to occur via a base flipping mechanism and is believed to be a general mechanism for all methyltransferases. If no str...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC407817/ https://ncbi.nlm.nih.gov/pubmed/15107490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh531 |
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