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Unusual 2-aminopurine fluorescence from a complex of DNA and the EcoKI methyltransferase
The methyltransferase, M.EcoKI, recognizes the DNA sequence 5′-AACNNNNNNGTGC-3′ and methylates adenine at the underlined positions. DNA methylation has been shown by crystallography to occur via a base flipping mechanism and is believed to be a general mechanism for all methyltransferases. If no str...
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| Опубликовано в: : | Nucleic Acids Res |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407817/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15107490/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh531 |
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