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Atomic force microscopy of the EcoKI Type I DNA restriction enzyme bound to DNA shows enzyme dimerization and DNA looping

Atomic force microscopy (AFM) allows the study of single protein–DNA interactions such as those observed with the Type I Restriction–Modification systems. The mechanisms employed by these systems are complicated and understanding them has proved problematic. It has been known for years that these en...

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Detalhes bibliográficos
Main Authors: Neaves, Kelly J., Cooper, Laurie P., White, John H., Carnally, Stewart M., Dryden, David T. F., Edwardson, J. Michael, Henderson, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665228/
https://ncbi.nlm.nih.gov/pubmed/19223329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp042
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