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Genetical genomics of Th1 and Th2 immune response in a baboon model of atherosclerosis risk factors

OBJECTIVE: CD4(+) T-cells mediate inflammation in atherosclerosis, but additive genetic effects on associated pathways of Th1 and Th2 immune response have not been described. We sought to characterize heritability, pleiotropy, and QTL effects on the expression of genes implicated in Th1 and Th2 immu...

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Main Authors: Vinson, A, Curran, JE, Johnson, MP, Dyer, TD, Moses, EK, Blangero, J, Cox, LA, Rogers, J, Havill, LM, VandeBerg, JL, Mahaney, MC
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176804/
https://ncbi.nlm.nih.gov/pubmed/21762917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2011.06.015
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