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Genetical genomics of Th1 and Th2 immune response in a baboon model of atherosclerosis risk factors

OBJECTIVE: CD4(+) T-cells mediate inflammation in atherosclerosis, but additive genetic effects on associated pathways of Th1 and Th2 immune response have not been described. We sought to characterize heritability, pleiotropy, and QTL effects on the expression of genes implicated in Th1 and Th2 immu...

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Detalhes bibliográficos
Main Authors: Vinson, A, Curran, JE, Johnson, MP, Dyer, TD, Moses, EK, Blangero, J, Cox, LA, Rogers, J, Havill, LM, VandeBerg, JL, Mahaney, MC
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176804/
https://ncbi.nlm.nih.gov/pubmed/21762917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2011.06.015
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