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A PLEIOTROPIC QTL ON 2p INFLUENCES SERUM LP-PLA(2) ACTIVITY AND LDL CHOLESTEROL CONCENTRATION IN A BABOON MODEL FOR THE GENETICS OF ATHEROSCLEROSIS RISK FACTORS

Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)), the major portion of which is bound to low-density lipoprotein, is an independent biomarker of cardiovascular disease risk. To search for common genetic determinants of variation in both Lp-PLA(2) activity and LDL cholesterol (LDL-C) concentrati...

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Detalhes bibliográficos
Main Authors: Vinson, A., Mahaney, M.C., Cox, L.A., Rogers, J., VandeBerg, J.L., Rainwater, D.L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289511/
https://ncbi.nlm.nih.gov/pubmed/17767937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2007.07.014
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