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The non-coding RNA Mistral activates Hoxa6 and Hoxa7 expression and stem cell differentiation by recruiting Mll1 to chromatin
The epigenetic activator Mixed lineage leukemia 1 (Mll1) is paramount for embryonic development and hematopoiesis. Here we demonstrate that the long, non-coding RNA (lncRNA) Mistral (Mira) activates transcription of the homeotic genes Hoxa6 and Hoxa7 in mouse embryonic stem cells (mESC) by recruitin...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3176448/ https://ncbi.nlm.nih.gov/pubmed/21925392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.08.019 |
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