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The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific.

Normalized dose response-curves for transcriptional activation of reporter genes were obtained by co-transfecting them with increasing amounts of wild-type (wt) progesterone (PR), glucocorticoid (GR) and oestrogen (ER) expression vectors. Marked differences in both shape and magnitude of the stimula...

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Detalhes bibliográficos
Main Authors: Bocquel, M T, Kumar, V, Stricker, C, Chambon, P, Gronemeyer, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317644/
https://ncbi.nlm.nih.gov/pubmed/2717402
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