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Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection

Cytokine storm during viral infection is a prospective predictor of morbidity and mortality, yet the cellular sources remain undefined. Here, using genetic and chemical tools to probe functions of the S1P(1) receptor, we elucidate cellular and signaling mechanisms that are important in initiating cy...

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Detalhes bibliográficos
Main Authors: Teijaro, John R., Walsh, Kevin B., Cahalan, Stuart, Fremgen, Daniel M., Roberts, Edward, Scott, Fiona, Martinborough, Esther, Peach, Robert, Oldstone, Michael B.A., Rosen, Hugh
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176439/
https://ncbi.nlm.nih.gov/pubmed/21925319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.08.015
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