Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS).

We have improved the "polymerase chain reaction" (PCR) to permit rapid analysis of any known mutation in genomic DNA. We demonstrate a system, ARMS (Amplification Refractory Mutation System), that allows genotyping solely by inspection of reaction mixtures after agarose gel electrophoresis...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Newton, C R, Graham, A, Heptinstall, L E, Powell, S J, Summers, C, Kalsheker, N, Smith, J C, Markham, A F
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1989
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317639/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2785681/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.7.2503
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