Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS).

We have improved the "polymerase chain reaction" (PCR) to permit rapid analysis of any known mutation in genomic DNA. We demonstrate a system, ARMS (Amplification Refractory Mutation System), that allows genotyping solely by inspection of reaction mixtures after agarose gel electrophoresis...

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Detalhes bibliográficos
Main Authors: Newton, C R, Graham, A, Heptinstall, L E, Powell, S J, Summers, C, Kalsheker, N, Smith, J C, Markham, A F
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317639/
https://ncbi.nlm.nih.gov/pubmed/2785681
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