The detection of K-ras mutations in colorectal cancer using the amplification-refractory mutation system.

A total of 301 colorectal carcinoma (CRC) archival samples were analysed using the amplification-refractory mutation system (ARMS). Each sample was examined to determine the mutation status of codons 12 and 13 of the K-ras oncogene. The results from direct DNA sequence analysis carried out on 30 of...

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Autors principals: Fox, J. C., England, J., White, P., Ellison, G., Callaghan, K., Charlesworth, N. R., Hehir, J., McCarthy, T. L., Smith-Ravin, J., Talbot, I. C., Snary, D., Northover, J. M., Newton, C. R., Little, S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1998
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150152/
https://ncbi.nlm.nih.gov/pubmed/9579832
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