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Detection of single DNA base differences by competitive oligonucleotide priming.
Synthetic DNA oligonucleotides can serve as efficient primers for DNA synthesis even when there is a single base mismatch between the primers and the corresponding DNA template. However, when the primer-template annealing is carried out with a mixture of primers and at low stringency the binding of...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1989
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC317634/ https://ncbi.nlm.nih.gov/pubmed/2717399 |
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