Detection of single-base mutation of DNA oligonucleotides with different lengths by terahertz attenuated total reflection microfluidic cell

Many human genetic diseases are caused by single-base mutation in the gene sequence. Since DNA molecules with single-base mutation are extremely difficult to differentiate, existing detection methods are invariably complex and time-consuming. We propose a new label-free and fast terahertz (THz) spec...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomed Opt Express
Prif Awduron: Tang, Mingjie, Zhang, Mingkun, Xia, Liangping, Yang, Zhongbo, Yan, Shihan, Wang, Huabin, Wei, Dongshan, Du, Chunlei, Cui, Hong-Liang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Optical Society of America 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510857/
https://ncbi.nlm.nih.gov/pubmed/33014620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.400487
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