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Phenethyl pyridines with non-polar internal substitutents as selective ligands for estrogen receptor beta

To create estrogen receptor beta (ERβ)-selective ligands with improved biological characteristics, we have extended our investigations of structurally simple bibenzyl-core ligands by preparing a series of compounds in which one phenol is replaced by a 3-hydroxy-pyridine ring. These phenethyl pyridin...

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Detalhes bibliográficos
Main Authors: Waibel, Michael, Kieser, Karen J., Carlson, Kathryn E., Stossi, Fabio, Katzenellenbogen, Benita S., Katzenellenbogen, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176332/
https://ncbi.nlm.nih.gov/pubmed/19394116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2009.03.013
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