Receptor-Mediated Endocytosis of α-Galactosidase A in Human Podocytes in Fabry Disease

Injury to the glomerular podocyte is a key mechanism in human glomerular disease and podocyte repair is an important therapeutic target. In Fabry disease, podocyte injury is caused by the intracellular accumulation of globotriaosylceramide. This study identifies in the human podocyte three endocytic...

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Autors principals: Prabakaran, Thaneas, Nielsen, Rikke, Larsen, Jakob V., Sørensen, Søren S., Rasmussen, Ulla Feldt-, Saleem, Moin A., Petersen, Claus M., Verroust, Pierre J., Christensen, Erik I.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176300/
https://ncbi.nlm.nih.gov/pubmed/21949853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025065
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