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Receptor-Mediated Endocytosis of α-Galactosidase A in Human Podocytes in Fabry Disease

Injury to the glomerular podocyte is a key mechanism in human glomerular disease and podocyte repair is an important therapeutic target. In Fabry disease, podocyte injury is caused by the intracellular accumulation of globotriaosylceramide. This study identifies in the human podocyte three endocytic...

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Detalhes bibliográficos
Main Authors: Prabakaran, Thaneas, Nielsen, Rikke, Larsen, Jakob V., Sørensen, Søren S., Rasmussen, Ulla Feldt-, Saleem, Moin A., Petersen, Claus M., Verroust, Pierre J., Christensen, Erik I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176300/
https://ncbi.nlm.nih.gov/pubmed/21949853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025065
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