Receptor-Mediated Endocytosis of α-Galactosidase A in Human Podocytes in Fabry Disease

Injury to the glomerular podocyte is a key mechanism in human glomerular disease and podocyte repair is an important therapeutic target. In Fabry disease, podocyte injury is caused by the intracellular accumulation of globotriaosylceramide. This study identifies in the human podocyte three endocytic...

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Bibliografski detalji
Glavni autori: Prabakaran, Thaneas, Nielsen, Rikke, Larsen, Jakob V., Sørensen, Søren S., Rasmussen, Ulla Feldt-, Saleem, Moin A., Petersen, Claus M., Verroust, Pierre J., Christensen, Erik I.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176300/
https://ncbi.nlm.nih.gov/pubmed/21949853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025065
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