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Evidence Implicating the Ras Pathway in Multiple CD28 Costimulatory Functions in CD4(+) T Cells

CD28 costimulation is a critical event in the full activation of CD4(+) T cells that augments cytokine gene transcription, promotes cytokine mRNA stability, prevents induction of anergy, increases cellular metabolism, and increases cell survival. However, despite extensive biochemical analysis of th...

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Autors principals: Janardhan, Sujit V., Praveen, Kesavannair, Marks, Reinhard, Gajewski, Thomas F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176298/
https://ncbi.nlm.nih.gov/pubmed/21949793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024931
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