Interferon-γ Exacerbates Dry Eye–Induced Apoptosis in Conjunctiva through Dual Apoptotic Pathways

PURPOSE. To investigate the role of interferon (IFN)-γ in dry eye–associated conjunctival apoptosis. METHODS. Desiccating stress (DS) was created in C57BL/6 (B6) and C57BL/6 IFN-γ-knockout (B6γKO) mice. A separate group of mice of both strains also received subconjunctival injections of exogenous IF...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaobo, Chen, Wei, De Paiva, Cintia S., Corrales, Rosa M., Volpe, Eugene A., McClellan, Andrew J., Farley, William J., Li, De-Quan, Pflugfelder, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176027/
https://ncbi.nlm.nih.gov/pubmed/21474767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-7081
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