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Increased Neovascularization in Mice Lacking Tissue Inhibitor of Metalloproteinases-3

PURPOSE. Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a matrix-bound inhibitor of matrix metalloproteinases (MMPs). The authors have previously determined a novel function of TIMP-3 to inhibit vascular endothelial growth factor (VEGF)-mediated angiogenesis. Here, the authors examined the in...

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Detalhes bibliográficos
Main Authors: Ebrahem, Quteba, Qi, Jian Hua, Sugimoto, Masahiko, Ali, Mariya, Sears, Jonathan E., Cutler, Alecia, Khokha, Rama, Vasanji, Amit, Anand-Apte, Bela
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175998/
https://ncbi.nlm.nih.gov/pubmed/21282576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5899
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