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Overexpression of Pax6 in Mouse Cornea Directly Alters Corneal Epithelial Cells: Changes in Immune Function, Vascularization, and Differentiation

PURPOSE. To assess whether Pax6 functions directly in the cornea, a corneal-preferred promoter was used to overexpress Pax6 specifically in the cornea. METHODS. Transgenic mice harboring a construct containing mouse Pax6 coding sequences fused downstream of the aldehyde dehydrogenase 3a1 (Aldh3a1) p...

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Détails bibliographiques
Auteurs principaux: Davis, Janine, Piatigorsky, Joram
Format: Artigo
Langue:Inglês
Publié: Association for Research in Vision and Ophthalmology, Inc. 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175973/
https://ncbi.nlm.nih.gov/pubmed/21447684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6726
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