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Increased Corneal Epithelial Turnover Contributes to Abnormal Homeostasis in the Pax6(+/−) Mouse Model of Aniridia
We aimed to test previous predictions that limbal epithelial stem cells (LESCs) are quantitatively deficient or qualitatively defective in Pax6(+/−) mice and decline with age in wild-type (WT) mice. Consistent with previous studies, corneal epithelial stripe patterns coarsened with age in WT mosaics...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3742784/ https://ncbi.nlm.nih.gov/pubmed/23967157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071117 |
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