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The synthesis of 2-pyrimidinone nucleosides and their incorporation into oligodeoxynucleotides.

The synthesis of 1-(beta-D-2'-deoxyribosyl)-2-pyrimidinone (dK) and its 5-methyl derivative (d5) from 2'-deoxycytidine or 2'-deoxythymidine, respectively, via silver oxide oxidation of 4-hydrazinopyrimidines is described. The necessary hydrazine substituted pyrimidine nucleosides have...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gildea, B, McLaughlin, L W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1989
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317595/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2704620/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.6.2261
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